Gunn R A, Gallager H S
Cancer. 1980 Aug 1;46(3):590-4. doi: 10.1002/1097-0142(19800801)46:3<590::aid-cncr2820460327>3.0.co;2-q.
Four vulvectomy specimens from patients with vulvar Paget's disease were studied by means of subserial total sectioning. In each case, the extent of histologically demonstrable disease was far greater than that of the visible lesion, the outline of the involved area was highly irregular, and multiple foci of disease were present. The implications of the findings for treatment selection, intraoperative management, and histogenesis are discussed.
对4例外阴佩吉特病患者的外阴切除标本进行了连续亚全切片研究。在每例病例中，组织学上可证实的病变范围远远大于可见病变，受累区域的轮廓极不规则，且存在多个病灶。讨论了这些发现对治疗选择、术中处理及组织发生的意义。
