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法国牛群中的牛白血病病毒特异性抗体。III. 用于检测感染牛白血病病毒动物的BLV-gp 51放射免疫测定法的患病率。

Bovine leukemia virus-specific antibodies in French cattle. III. Prevalence of the BLV-gp 51 radioimmunoassay for the detection of BLV-infected animals.

作者信息

Levy D, Deshayes L, Parodi A L, Levy J P

出版信息

Int J Cancer. 1980 Jan 15;25(1):147-52. doi: 10.1002/ijc.2910250120.

DOI:10.1002/ijc.2910250120
PMID:6249762
Abstract

The control of the spread of BLV infection among cattle requires very sensitive methods of detection. The BLV-gp51 radioimmunoassay presents great advantages over the other serological methods, including the BLV-p24 radioimmunoassay. This is clear from studies of normal animals from the high-leukemia-incidence region which show that anti-gp51 antibodies reach higher titers than anti-p24 or may even exist alone. Moreover, a sequential survey reveals that the anti-gp antibodies appear earlier. On the other hand, it was not possible to detect a viral antigen expression in the tissues of the infected animals.

摘要

控制牛白血病病毒(BLV)在牛群中的传播需要非常灵敏的检测方法。与其他血清学方法相比,包括BLV-p24放射免疫测定法,BLV-gp51放射免疫测定法具有很大优势。这在对高白血病发病率地区正常动物的研究中很明显,研究表明抗gp51抗体的滴度高于抗p24抗体,甚至可能单独存在。此外,连续调查显示抗gp抗体出现得更早。另一方面,在受感染动物的组织中未能检测到病毒抗原表达。

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