培养的人淋巴细胞对人生长激素的区室化作用 - Suppr | 超能文献

Compartmentalization of human growth hormone by cultured human lymphocytes.

作者信息

Rosenfeld R G, Hintz R L

出版信息

J Clin Endocrinol Metab. 1980 Aug;51(2):368-75. doi: 10.1210/jcem-51-2-368.

DOI:10.1210/jcem-51-2-368

Abstract

摘要

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Regulation of insulin-like growth factor I gene expression by growth hormone.生长激素对胰岛素样生长因子I基因表达的调控

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Intracellular potassium depletion in IM-9 lymphocytes suppresses the slowly dissociating component of human growth hormone binding and the down-regulation of its receptors but does not affect insulin receptors.IM-9淋巴细胞内的钾离子耗竭会抑制人生长激素结合的缓慢解离成分及其受体的下调，但不影响胰岛素受体。

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Receptor-binding and down-regulatory properties of 22000-Mr human growth hormone and its natural 20000-Mr variant on IM-9 human lymphocytes.22000道尔顿的人生长激素及其天然20000道尔顿变体对IM-9人淋巴细胞的受体结合和下调特性

Biochem J. 1985 Jan 15;225(2):283-9. doi: 10.1042/bj2250283.