[Effect of adenosine cyclic monophosphate on insulin secretion in healthy rats and in those with alloxan diabetes].

Studies on rats and dogs demonstrated exogenous cAMP to aid elevation of the blood insulin level in healthy animals and, to a lesser extent, in the animals with a mild course of diabetes mellitus caused by alloxan damage of beta-cells. In case of a severe course of diabetes mellitus exogenous cAMP produced no stimulating action on the insulin secretion.