当恒河猴群体中的一些成员摄入Δ⁹四氢大麻酚或右旋苯丙胺时，群体成员之间的间距会发生变化。

The spacing of rhesus monkey troops changes when a few group members receive delta 9THC or D-amphetamine.

作者信息

Burgess J W, Witt P N, Phoebus E, Weisbard C

出版信息

Pharmacol Biochem Behav. 1980 Jul;13(1):121-4. doi: 10.1016/0091-3057(80)90130-6.

Abstract

Free ranging troops of 18--25 rhesus macaques were housed in large enclosures where a few higher-ranking monkeys were given psychotropic agents (delta 9THC: 4 mg/kg or d-amphetamine: 2 mg/kg). Measures of group spacing were (1) mean distance between all animals. (2) daily variance in mean distance, (3) nearest neighbor distance, (4) daily variance in nearest neighbor distance, (5) index of clumping (S2/mean ratio), (6) % touching, and (7) % movement/2 sec. When 3--4 animals were drugged, the entire group moved closer together and distances were more variable. Acute changes after the first week of delta 9THC and effects after delta 9THC withdrawal were seen in two experiments. Chronic behavioral changes were found for d-amphetamine and in one delta 9THC experiment.

摘要

18至25只恒河猴组成的自由放养猴群被安置在大型围栏中，几只等级较高的猴子被给予精神药物（Δ9四氢大麻酚：4毫克/千克或右旋苯丙胺：2毫克/千克）。群体间距的测量指标有：（1）所有动物之间的平均距离；（2）平均距离的每日方差；（3）最近邻距离；（4）最近邻距离的每日方差；（5）聚集指数（S2/均值比）；（6）接触百分比；（7）每2秒的移动百分比。当3至4只动物被下药后，整个猴群会靠得更近，距离变化也更大。在两项实验中观察到了Δ9四氢大麻酚给药第一周后的急性变化以及停药后的影响。在一项右旋苯丙胺实验和一项Δ9四氢大麻酚实验中发现了慢性行为变化。