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钙结石病中高钙尿症的诊断(作者译)

[Diagnosis of hypercalciuria in calcium nephrolithiasis (author's transl)].

作者信息

Joost J, Puschendorf B

出版信息

Dtsch Med Wochenschr. 1980 Jul 11;105(28):988-92. doi: 10.1055/s-2008-1070797.

Abstract

An increased calcium excretion in 24-hour urine was found in 32 of 42 out-patients with recurrent calcium nephrolithiasis (calcium excretion > 300 mg in males, > 250 mg in females). Subsequent hospitalization of the 32 patients revealed the following diagnosis after a calcium tolerance test: absorptive hypercalciuria in 18, renal hypercalciuria in 4, primary hyperparathyroidism in 2 and dietary hypercalciuria in 7. Normocalciuria in 10 out-patients was confirmed in 6; in one instance there was, however, primary hyperparathyroidism, in 3 there was absorptive hypercalciuria. In one patient it was not possible to classify the hypercalciuria. Total as well as nephrogenic cAMP showed wide scatter and was unsuitable, therefore, in differential diagnosis. In 2 of 3 cases of hyperparathyroidism the serum level of parathormone was distinctly elevated.

摘要

42例复发性钙肾结石门诊患者中,32例24小时尿钙排泄增加(男性钙排泄>300mg,女性>250mg)。随后,这32例患者住院,在进行钙耐量试验后得出以下诊断:18例为吸收性高钙尿症,4例为肾性高钙尿症,2例为原发性甲状旁腺功能亢进,7例为饮食性高钙尿症。10例门诊患者的正常钙尿症在6例中得到证实;然而,其中1例为原发性甲状旁腺功能亢进,3例为吸收性高钙尿症。1例患者的高钙尿症无法分类。总环磷酸腺苷(cAMP)和肾源性cAMP均显示出广泛的离散度,因此不适用于鉴别诊断。3例甲状旁腺功能亢进患者中有2例甲状旁腺激素血清水平明显升高。

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