Shigenobu M, Kay J H, Mendez M, Zubiate P, Vanstrom N, Yokoyama T
J Thorac Cardiovasc Surg. 1978 Feb;75(2):290-5.
Pure mitral insufficiency associated with secundum atrial septal defect is not an unusual finding. Thirteen patients with significant mitral insufficiency and an associated secundum defect were operated upon. Two of these patients also had severe tricuspid insufficiency. The mitral valve was repaired in 12 patients and replaced in one. The tricuspid valve was reapired in the two patients with associated tricuspid insufficiency. There were two early deaths due to mediastinitis and one late death due to a cerebral embolus in the only patient who had valve replacement; this patient died 3 years after the operation. It is concluded that mitral and tricuspid valve repair should be performed for patients with significant mitral and tricuspid insufficiency associated with atrial septal defect of the secundum variety. Replacement of the values should be avoided if possible.
继发孔型房间隔缺损合并单纯二尖瓣关闭不全并非罕见。对13例有明显二尖瓣关闭不全及相关继发孔缺损的患者进行了手术。其中2例患者还伴有严重三尖瓣关闭不全。12例患者的二尖瓣进行了修复,1例进行了置换。2例合并三尖瓣关闭不全的患者的三尖瓣进行了修复。有2例因纵隔炎早期死亡,1例接受瓣膜置换的患者因脑栓塞晚期死亡;该患者术后3年死亡。结论是,对于继发孔型房间隔缺损合并明显二尖瓣和三尖瓣关闭不全的患者,应进行二尖瓣和三尖瓣修复。应尽可能避免瓣膜置换。