Grewe H E, Berndt V
Zentralbl Chir. 1980;105(6):384-97.
Tumours of the nervous system are rare. Clinical and therapeutic aspects are discussed with relation to 54 cases. The benign tumours of the peripheric nerves such as neurinomas and neurofibromas, show a high rate of malignant degeneration. For this reason, every tumour of the soft tissues has to be removed and should be examined by the pathologist. In cases of retroperitoneal and intestinal localisation an early diagnosis is frequently impossible. For differential diagnosis laparotomy or thoracotomy are always indicated. X-ray examinations of the kidneys, the thorax as well as the intestines and mesenteric vessels show satisfactory results. The neurogenic sarcomas and neuroblastomas are discovered late because of their hidden localisation and poor symptoms. The poor prognosis has not been improved by cytostatsis and radiation.
神经系统肿瘤较为罕见。本文结合54例病例对其临床和治疗方面进行了讨论。周围神经的良性肿瘤，如神经鞘瘤和神经纤维瘤，恶变率很高。因此，每一个软组织肿瘤都必须切除，并应由病理学家进行检查。对于腹膜后和肠道定位的病例，往往无法早期诊断。鉴别诊断时总是需要进行剖腹手术或开胸手术。对肾脏、胸部以及肠道和肠系膜血管进行X线检查，结果令人满意。神经源性肉瘤和神经母细胞瘤由于其隐匿的定位和不良症状而发现较晚。细胞抑制剂和放疗并未改善其不良预后。
