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[吗啡、β-内啡肽和甲硫氨酸脑啡肽对苹果螺神经元电活动的影响]

[Effect of morphine, beta-endorphin, and met-enkephalin on electrical activity of Helix pomatia snail neurons].

作者信息

Solntseva E I, Bulaev V M

出版信息

Zh Evol Biokhim Fiziol. 1980 Sep-Oct;16(5):425-9.

PMID:6252733
Abstract

Application of morphine and methionine-enkephaline using microionophoretic technique (20-100 nA, 1-15 sec) or perfusion (10(-7)--10(-6) M) caused inhibition of the impulsation, which in some of the cases was accompanied by hyperpolarization of the membrane and the decrease in its resistance, as well as by the reduction of EPSP's. The increase in impulsation with membrane depolarization was less frequent. beta-Endorphine (10(-7)--10(-6) M) caused a substantially longer inhibition of the impulse activity than morphine or met-enkephaline.

摘要

采用微离子电泳技术(20 - 100纳安,1 - 15秒)或灌流法(10⁻⁷ - 10⁻⁶摩尔)应用吗啡和甲硫氨酸脑啡肽会导致冲动发放受到抑制,在某些情况下还伴有膜超极化及其电阻降低,以及兴奋性突触后电位(EPSP)减小。随着膜去极化冲动发放增加的情况较少见。β-内啡肽(10⁻⁷ - 10⁻⁶摩尔)引起的冲动活动抑制比吗啡或甲硫氨酸脑啡肽持续时间长得多。

相似文献

1
[Effect of morphine, beta-endorphin, and met-enkephalin on electrical activity of Helix pomatia snail neurons].[吗啡、β-内啡肽和甲硫氨酸脑啡肽对苹果螺神经元电活动的影响]
Zh Evol Biokhim Fiziol. 1980 Sep-Oct;16(5):425-9.
2
[Effect of the opiate antagonist naloxone on the electrical activity of identified neurons in the edible snail].[阿片拮抗剂纳洛酮对可食用蜗牛中已鉴定神经元电活动的影响]
Nauchnye Doki Vyss Shkoly Biol Nauki. 1987(6):50-5.
3
[Selective reduction by morphine and enkephalins of depolarization induced by application of dopamine to Helix pomatia neurons].[吗啡和脑啡肽对多巴胺作用于苹果螺神经元所诱导的去极化的选择性抑制]
Neirofiziologiia. 1983;15(1):10-5.
4
Morphine and methionine-enkephalin: different effects on spontaneous and evoked neuronal firing in the mesencephalic reticular formation of the rat.吗啡和甲硫氨酸脑啡肽:对大鼠中脑网状结构自发和诱发神经元放电的不同影响。
J Pharmacol Exp Ther. 1980 May;213(2):355-63.
5
Modulation of peripheral adrenergic neurotransmission by methionine-enkephalin.甲硫氨酸脑啡肽对外周肾上腺素能神经传递的调节作用。
J Pharmacol Exp Ther. 1982 May;221(2):282-8.
6
[Effect of beta-endorphin, enkephalins and their synthetic analogs on the neuronal electrical activity of the respiratory center in the medulla oblongata].[β-内啡肽、脑啡肽及其合成类似物对延髓呼吸中枢神经元电活动的影响]
Biull Eksp Biol Med. 1984 Dec;98(12):687-90.
7
Effects of morphine and opioid peptides on sensitivity to acetylcholine of dialysed snail neurons.吗啡和阿片肽对透析的蜗牛神经元乙酰胆碱敏感性的影响。
Neuroscience. 1983 Apr;8(4):855-60. doi: 10.1016/0306-4522(83)90015-5.
8
Cyclic AMP, morphine, met-enkephalin and neuronal firing.环磷酸腺苷、吗啡、甲硫氨酸脑啡肽与神经元放电
J Pharmacol Exp Ther. 1981 Nov;219(2):496-504.
9
[Effect of adrenochrome on the neuronal membrane of the mollusk Helix pomatia].[肾上腺素色素对软体动物罗马蜗牛神经元膜的影响]
Biull Eksp Biol Med. 1982 Apr;93(4):64-6.
10
[Effect of theophylline on electrical activity of the bursting type in an identified edible snail neuron].
Neirofiziologiia. 1981;13(1):75-9.

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Neurotransmitter basis of mollusc behavior: control of choice between the orienting and the defense response to the presentation of an unfamiliar object.软体动物行为的神经递质基础:对陌生物体出现时定向反应和防御反应之间选择的控制。
Neurosci Behav Physiol. 1995 May-Jun;25(3):247-51. doi: 10.1007/BF02360213.