Tzipori S, Chandler D, Smith M, Makin T, Hennessy D
Aust Vet J. 1980 Jun;56(6):274-8. doi: 10.1111/j.1751-0813.1980.tb05723.x.
Some aspects of postweaning diarrhoea (PWD) in a piggery during the first week after early weaning were investigated. A haemolytic enterotoxigenic strain of E. coli (O149:K88:H10) was regularly recovered from piglets with PWD while rotavirus was demonstrated on a number of occasions. Prior to weaning piglets were either free of, or shed very few, haemolytic E. coli in their faeces. However, all piglets were excreting haemolytic E. coli between 5 and 7 days after weaning. The role of rotavirus in PWD was unclear. There appeared to be a direct relationship between serum antibodies to rotavirus in the slow at farrowing and those of the piglets soon after birth. The decline of maternal neutralising antibody to rotavirus coincided with the immediate postweaning period (3 to 5 weeks after birth). This was followed by an increase in antibody levels, 5 to 8 weeks after birth. There was no significant difference in the growth rate between affected and unaffected piglets over a period of 120 days. Medication of water during the first week after weaning had no significant effect on the incidence of PWD in the herd. A change in both the weaner diet and the weaning procedure reduced piglet mortality associated with PWD by more than half.
对早期断奶后第一周猪场断奶后腹泻（PWD）的某些方面进行了调查。从患有PWD的仔猪中经常分离出溶血性产肠毒素大肠杆菌菌株（O149:K88:H10），同时多次检测到轮状病毒。断奶前，仔猪粪便中要么没有溶血性大肠杆菌，要么排出的数量很少。然而，所有仔猪在断奶后5至7天均排出溶血性大肠杆菌。轮状病毒在PWD中的作用尚不清楚。分娩缓慢的母猪血清中抗轮状病毒抗体与仔猪出生后不久的抗体之间似乎存在直接关系。母体抗轮状病毒中和抗体的下降与断奶后即刻阶段（出生后3至5周）相吻合。随后在出生后5至8周抗体水平升高。在120天的时间里，受影响和未受影响的仔猪生长速度没有显著差异。断奶后第一周在饮水中添加药物对猪群中PWD的发病率没有显著影响。断奶仔猪日粮和断奶程序的改变使与PWD相关的仔猪死亡率降低了一半以上。
