影响石棉诱发间皮瘤发生率的治疗方法。
Treatments affecting the rate of asbestos-induced mesotheliomas.
作者信息
Wagner J C, Hill R J, Berry G, Wagner M M
出版信息
Br J Cancer. 1980 Jun;41(6):918-22. doi: 10.1038/bjc.1980.169.
Abstract
256 Wistar rats received a single injection into the right pleural cavity of UICC crocidolite in order to induce mesotheliomas. They were then given right intrapleural injectons of BCG, crystalline silica, talc, carrageenan or saline (as a control). There was no significant change in the mesothelioma rate in the rats exposed to BCG, silica or talc, but there was a 3-fold increase in mesothelioma incidence in the group injected with carrageenan.
摘要
256只Wistar大鼠右胸腔单次注射UICC标准蓝石棉以诱发间皮瘤。随后对它们进行右胸腔内注射卡介苗、结晶硅石、滑石粉、角叉菜胶或生理盐水（作为对照）。接触卡介苗、硅石或滑石粉的大鼠间皮瘤发生率无显著变化，但注射角叉菜胶的组中间皮瘤发生率增加了3倍。
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