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一位患有无法手术的乳腺癌的哺乳期母亲的乳汁中癌胚抗原水平升高。

Elevated carcinoembryonic antigen levels in the milk of a nursing mother with inoperable breast cancer.

作者信息

Bartal A H, Kahana L, Yarom J

出版信息

Cancer. 1980 Nov 1;46(9):2091-2. doi: 10.1002/1097-0142(19801101)46:9<2091::aid-cncr2820460930>3.0.co;2-d.

DOI:10.1002/1097-0142(19801101)46:9<2091::aid-cncr2820460930>3.0.co;2-d
PMID:6253050
Abstract

Carcinoembryonic antigen (CEA) determinations performed in the milk of a nursing mother with an inoperable breast cancer revealed a 10-15-fold higher level compared with CEA levels in the milk of healthy nursing women. CEA was highly elevated in the milk of the tumor-bearing breast (1100 +/- 100 ng/ml) and moderately elevated in the milk of the clinically nonaffected breast (700 +/- 50 ng/ml). However, serum CEA levels were within normal range (9.8 +/- 0.5 ng/ml). The various theoretical and practical implications of this finding, including considerations for early breast cancer detection, are discussed.

摘要

对一名患有无法手术的乳腺癌的哺乳期母亲乳汁中癌胚抗原(CEA)的检测发现,其乳汁中CEA水平比健康哺乳期女性乳汁中的CEA水平高10至15倍。患侧乳房乳汁中的CEA水平显著升高(1100±100 ng/ml),而健侧乳房乳汁中的CEA水平中度升高(700±50 ng/ml)。然而,血清CEA水平在正常范围内(9.8±0.5 ng/ml)。本文讨论了这一发现的各种理论和实际意义,包括对早期乳腺癌检测的考虑。

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