Bartal A H, Kahana L, Yarom J
Cancer. 1980 Nov 1;46(9):2091-2. doi: 10.1002/1097-0142(19801101)46:9<2091::aid-cncr2820460930>3.0.co;2-d.
Carcinoembryonic antigen (CEA) determinations performed in the milk of a nursing mother with an inoperable breast cancer revealed a 10-15-fold higher level compared with CEA levels in the milk of healthy nursing women. CEA was highly elevated in the milk of the tumor-bearing breast (1100 +/- 100 ng/ml) and moderately elevated in the milk of the clinically nonaffected breast (700 +/- 50 ng/ml). However, serum CEA levels were within normal range (9.8 +/- 0.5 ng/ml). The various theoretical and practical implications of this finding, including considerations for early breast cancer detection, are discussed.
对一名患有无法手术的乳腺癌的哺乳期母亲乳汁中癌胚抗原(CEA)的检测发现,其乳汁中CEA水平比健康哺乳期女性乳汁中的CEA水平高10至15倍。患侧乳房乳汁中的CEA水平显著升高(1100±100 ng/ml),而健侧乳房乳汁中的CEA水平中度升高(700±50 ng/ml)。然而,血清CEA水平在正常范围内(9.8±0.5 ng/ml)。本文讨论了这一发现的各种理论和实际意义,包括对早期乳腺癌检测的考虑。