Hubbard C J
J Reprod Fertil. 1980 Jul;59(2):351-5. doi: 10.1530/jrf.0.0590351.
Cyclic GMP, cAMP and total DNA levels were determined in whole hamster ovaries on each day of the 4-day cycle. Pro-oestrous ovaries were removed during the time of the preovulatory LH surge (confirmed by RIA). Cyclic AMP levels (pmol/mg DNA) were highest during pro-oestrous (1268.0 +/- 139 (s.e.m.)) and lowest during dioestrus 2 ( 266.9 +/- 22). Cyclic GMP (pmol/mg DNA levels were highest at dioestrus 2 (87.2 +/- 19) and lowest during oestrus (11.9 +/- 2). Similar patterns were obtained with total pmol/4 ovaries. However expressed, there was an inverse correlation of cAMP and cGMP at dioestrus 2 (P < 0.02) and pro-oestrus (P < 0.001). Cyclic GMP was inversely correlated with total DNA levels (P < 0.02) at oestrus and dioestrus 2.
在4天周期的每一天，测定全仓鼠卵巢中的环磷酸鸟苷（cGMP）、环磷酸腺苷（cAMP）和总DNA水平。在排卵前促黄体生成素（LH）峰出现时（通过放射免疫分析法确认）摘除动情前期的卵巢。环磷酸腺苷水平（皮摩尔/毫克DNA）在动情前期最高（1268.0±139（标准误）），在间情期2最低（266.9±22）。环磷酸鸟苷（皮摩尔/毫克DNA）水平在间情期2最高（87.2±19），在发情期最低（11.9±2）。4个卵巢的总皮摩尔数也得到了类似的模式。无论如何表示，在间情期2（P<0.02）和动情前期（P<0.001），cAMP和cGMP呈负相关。在发情期和间情期2，环磷酸鸟苷与总DNA水平呈负相关（P<0.02）。
