Laxenaire M C, Sigiel M, Monert-Vautrin D A, Moeller R, Chastel A
Ann Anesthesiol Fr. 1976;17(2):85-90.
Eighteen grave anaphylactic accidents arising during induction or during anaesthesia, are analysed. By order of frequency, the clinical signs are cutaneous manifestations (70 p. 100 of the cases), bronchospasm (65 p. 100), cardiovascular collapse (45 p. 100). In four cases, cardiac arrest occurred. The course was always favourable, with no after-effects. Immuno-allergic tests enabled one to make the diagnosis of true anaphylaxis in eight cases (seven shocks due to succinylcholine, one due to propanidide), of non specific histamine-liberation in five cases; in the other cases, it was impossible to express an opinion.
分析了18例诱导期或麻醉期间发生的严重过敏事故。按出现频率排序,临床症状依次为皮肤表现(占病例的70%)、支气管痉挛(65%)、心血管虚脱(45%)。有4例发生心脏骤停。病程总是向好,无后遗症。免疫过敏试验使8例得以诊断为真正的过敏反应(7例由琥珀酰胆碱引起休克,1例由丙胺卡因引起),5例为非特异性组胺释放;在其他病例中,无法做出判断。