用烷基亚硝基脲在肋突螈（Pleurodeles waltlii）中诱导肿瘤（作者译）
[Tumour induction with alkyl-nitrosoureas in ribbed newts (Pleurodeles waltlii) (author's transl)].
作者信息
Jänisch W, Schmidt T
出版信息
Arch Geschwulstforsch. 1980;50(3):253-65.
PMID:6254465
Abstract
A search for animal models in the field of environmental carcinogenesis was performed. 50 adult ribbed newts were exposed to methyl- and ethylnitrosoureas. In 10 animals fibro- and hemangiosarcomas, nephroblastomas and a cavernous hemangioma were induced. No tumors of the nervous system occurred.
摘要
在环境致癌领域开展了动物模型的研究。50只成年肋突螈暴露于甲基亚硝基脲和乙基亚硝基脲。10只动物诱发了纤维肉瘤、血管肉瘤、肾母细胞瘤和海绵状血管瘤。未出现神经系统肿瘤。
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