Padmalatha C, Harruff R C, Ganick D, Hafez G B
Arch Pathol Lab Med. 1980 Dec;104(12):649-50.
Gliomas of the CNS associated with tuberous sclerosis have been well documented; malignant degeneration to glioblastoma multiforme, however, is rare. We studied a 17-year-old boy with stigmata of tuberous sclerosis and a cerebral glioblastoma multiforme. The rarity of this occurrence suggests that neoplasms arising from hamartomas may behave differently than those CNS tumors that arise apparently de novo.
中枢神经系统中与结节性硬化症相关的胶质瘤已有充分记录；然而，恶变为多形性胶质母细胞瘤的情况却很罕见。我们研究了一名患有结节性硬化症体征和脑多形性胶质母细胞瘤的17岁男孩。这种情况的罕见性表明，由错构瘤引发的肿瘤可能与那些明显新发的中枢神经系统肿瘤表现不同。
