Hori T, Nakashima T, Kiyohara T, Shibata M, Hori N
Neurosci Lett. 1980 Nov;20(2):171-5. doi: 10.1016/0304-3940(80)90141-x.
Extracellular single-unit activities of thermosensitive neurons were recorded from the medial preoptic area in rat's hypothalamic slices in vitro. Of 256 preoptic units, 74 were warm-units which increased firing rates in response to a rise in slice temperature and 16 units were cold-units having the opposite type of thermosensitivity. Eighteen of 23 warm-units and 3 of 4 cold-units retained their thermosensitivities during perfusion with Ca2+-free/high Mg2+ salt solution. The thermosensitivities of the remaining 5 warm-units were reversibly abolished in the Ca2+ deficient medium. The results suggest that some warm- and cold-sensitive neurons in the medial preoptic area have an inherent thermosensitivity.
在体外大鼠下丘脑切片的内侧视前区记录了热敏神经元的细胞外单单位活动。在256个视前区单位中，74个是温敏单位，其放电频率随切片温度升高而增加，16个单位是冷敏单位，具有相反类型的热敏性。23个温敏单位中的18个和4个冷敏单位中的3个在无钙/高镁盐溶液灌注期间保留了它们的热敏性。其余5个温敏单位的热敏性在缺钙培养基中被可逆地消除。结果表明，内侧视前区的一些温敏和冷敏神经元具有内在的热敏性。
