Lachowicz L, Janiszewska G, Wojtkowiak R
Acta Physiol Pol. 1980 May-Jun;31(3):261-7.
Values of cyclic AMP, DNA and protein content were determined in six regions of the rat brain: cerebral cortex, hippocampus, midbrain, thalamus with hypothalamus, cerebellum, and medulla. The obtained results indicated significant differences in the levels of protein in several areas of rat brain. There is some relationship between the changes in the content of DNA and cyclic AMP in these regions of the brain. These observations support the view that adenosine 3': 5'-monophosphate can play a positive role in regulating DNA synthesis in rat brain tissue.
测定了大鼠脑六个区域中环状单磷酸腺苷、DNA和蛋白质的含量:大脑皮层、海马体、中脑、丘脑与下丘脑、小脑和延髓。所得结果表明大鼠脑的几个区域中蛋白质水平存在显著差异。在脑的这些区域中,DNA含量的变化与环状单磷酸腺苷之间存在某种关系。这些观察结果支持这样一种观点,即3':5'-单磷酸腺苷在调节大鼠脑组织中的DNA合成方面可发挥积极作用。