The effect of 1,1,3-tricyano-2-amino-1-propene (TCAP) on RNA synthesis in chick embryo sciatic nerves.
作者信息
Dreiling C E
出版信息
Res Commun Chem Pathol Pharmacol. 1978 Jan;19(1):169-72.
PMID:625587
Abstract
Injections of 1,1,3-tricyano-2-amino-1-propene (TCAP) into chick embryos increases the synthesis of the myelin enzyme 2',3'-cyclic nucleotide 3'-phosphohydrolase (CNP). Whether this increase is associated with altered RNA synthesis was investigated by examining pulse 3H-uridine labelled RNA from in ovo and in vitro TCAP treated sciatic nerves. Characterization of the resultant TCAP-RNAs by polyacrylamide gel electrophoresis revealed that they met several criteria of messenger-RNA.
摘要
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