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[哇巴因不敏感的钠差异通量与溶液中钠浓度之间的关系]

[Relation between ouabain-insensitive differential sodium flux and sodium concentrations in solution].

作者信息

Ambartsumian T G, Adamian S Ia, Marikian G G

出版信息

Biofizika. 1980 Nov-Dec;25(6):1037-40.

PMID:6256008
Abstract

The dependence of net sodium ion flux on the external sodium concentration was studied under the inhibition of the sodium pump. A steady state balance of sodium ion fluxes occurred at external sodium concentration differing from the calculated one, therefore the existence of a non-diffusion component of sodium ion flux was evident. It was shown that the non-diffusion ouabain-insensitive sodium ion flux consisted of the sodium efflux not connected with chlorine efflux or potassium influx, and the sodium influx connected, perhaps, with potassium efflux.

摘要

在钠泵受抑制的情况下,研究了净钠离子通量对细胞外钠离子浓度的依赖性。在与计算值不同的细胞外钠离子浓度下,钠离子通量达到了稳态平衡,因此钠离子通量存在非扩散成分是显而易见的。结果表明,非扩散性哇巴因不敏感的钠离子通量包括与氯离子外流或钾离子内流无关的钠离子外流,以及可能与钾离子外流有关的钠离子内流。

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