Junod A F
Schweiz Med Wochenschr. 1978 Feb 25;108(8):260-2.
The relationship between the development of pulmonary emphysema and the presence of proteolytic enzymes with elastolytic properties released by polymorphonuclear leukocytes or by alveolar macrophages is briefly reviewed. The possible role of various antiproteolytic substances present in the lung is also described. The pathogenesis of pulmonary emphysema is discussed in the light of hypotheses recently put forward implicating an excess of proteolytic factors and/or a relative or absolute lack of protection substances.
本文简要回顾了肺气肿的发展与多形核白细胞或肺泡巨噬细胞释放的具有弹性溶解特性的蛋白水解酶之间的关系。还描述了肺中存在的各种抗蛋白水解物质的可能作用。根据最近提出的涉及蛋白水解因子过多和/或保护物质相对或绝对缺乏的假说，对肺气肿的发病机制进行了讨论。
