钙离子对海兔神经元中乙酰胆碱敏感通道的作用。

Action of calcium ions on acetylcholine-sensitive channels in Aplysia neurones.

Marty A

J Physiol (Paris). 1980 Sep;76(5):523-7.

Abstract

This work deals with the effects of external divalent ions on the values of the mean open time, tau, and of the elementary current, iel, of channels activated by acetylcholine in Aplysia neurones. The action of Ca is mainly considered. 2. Ca ions were found to prolong tau and decrease iel under various experimental conditions. In isotonic Ca solution, tau is 12 times larger than in isotonic Na solution (divalent free sea water). On the other hand, iel is about 8 times smaller in the first solution than in the second. 3. A quantitative analysis of these effects is presented.

摘要

本研究探讨了外部二价离子对海兔神经元中由乙酰胆碱激活的通道的平均开放时间（τ）值和单通道电流（iel）值的影响。主要考虑了钙离子的作用。2. 在各种实验条件下，发现钙离子可延长τ并降低iel。在等渗钙溶液中，τ比在等渗钠溶液（无二价离子的海水）中长12倍。另一方面，第一种溶液中的iel比第二种溶液中的小约8倍。3. 对这些影响进行了定量分析。