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[致低血糖胰岛细胞瘤。手术期间血糖和胰岛素水平的测定。7例结果(作者译)]

[Hypoglycemia-inducing islet cell tumors. Measurement of blood glucose and insulin levels during operation. Results in seven cases (author's transl)].

作者信息

Parneix M, Lotte P, Fabre P, de Coninck L

出版信息

Sem Hop. 1980;56(45-46):1913-7.

PMID:6256901
Abstract

The identification of hypoglycemic langerhans tumours by the surgeon, being sometimes difficult, per-operative quantity determinations of the glycemia and insulinemia levels help to ensure that all the insulino-secretory tissue has been removed. The technical protocol described includes an excess of glucids. In the 5 cases of adenomas, between 30 and 60 minutes after exeresis, a distinct increase in glycemia was noted (on average 1,25 g/l) in comparison to the initial level; this increase was not however significant in the 2 observations of adenomatous hyperplasia. Following the removal of the lesion, the fall in insulinemia is also more noticeable in adenomas (reaching 75,8 per cent of the initial level) than in adenomatous hyperplasia. Nonetheless, the fall in the latter is still considerable (42,4 per cent). This examination would be the best test, excvept that the results are known only after the operation. The 7 patients operated on recovered after 2 enucleo-excisions, and 5 isthmo-corporal-caudal splenopancreatectomies, the average post-operative period reaching 4 years.

摘要

外科医生识别低血糖性朗格汉斯细胞瘤有时会很困难,术中测定血糖和胰岛素血症水平有助于确保所有胰岛素分泌组织均已被切除。所描述的技术方案包括过量的糖类。在5例腺瘤病例中,切除术后30至60分钟,与初始水平相比,血糖明显升高(平均1.25 g/l);然而,在2例腺瘤样增生观察病例中,这种升高并不显著。切除病变后,腺瘤患者胰岛素血症的下降也比腺瘤样增生患者更明显(降至初始水平的75.8%)。尽管如此,后者的下降仍然相当可观(42.4%)。这项检查将是最佳测试,只是结果要在手术后才知道。7例接受手术的患者在2次摘除切除和5次峡部-体部-尾部脾胰切除术后康复,术后平均时间达4年。

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1
[Hypoglycemia-inducing islet cell tumors. Measurement of blood glucose and insulin levels during operation. Results in seven cases (author's transl)].[致低血糖胰岛细胞瘤。手术期间血糖和胰岛素水平的测定。7例结果(作者译)]
Sem Hop. 1980;56(45-46):1913-7.
2
[Hypoglycemic tumors (radio-immunological study)].
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[Hypoglycemia-inducing islet cell tumors. Measurement of blood glucose and insulin levels during operation. Results in seven cases (author's transl)].[低血糖诱导性胰岛细胞瘤。手术期间血糖和胰岛素水平的测定。7例结果(作者译)]
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Congenital islet cell adenoma causing hypoglycemia in a newborn.先天性胰岛细胞瘤导致新生儿低血糖。
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[A case of double insulinoma operated on twice. Study on the behavior of glycemia and insulinemia].[一例两次接受手术治疗的双胰岛素瘤病例。血糖和胰岛素血症行为研究]
Rev Clin Esp. 1975 Dec 31;139(6):563-70.