Bauters F, Jouet J P
Sem Hop. 1980;56(45-46):1963-7.
Forty febrile patients during several hematologic diseases (28 acute leukemias, 8 lymphocytic chronic leukemias, 3 drug induced agranulocytosis, 1 myeloid aplasia) received intensive combination antibiotherapy including cefoxitin (with gentamicin in all cases : Carbenicillin was added in 17 cases). Thirty-five patients had severe neutropenia before treatment. Infection's regression was obtained in 35 cases (in spite of persistence of neutropenia in 20 cases). No local, general or biological toxicity was observed.
40例患有多种血液系统疾病的发热患者(28例急性白血病、8例淋巴细胞性慢性白血病、3例药物性粒细胞缺乏症、1例骨髓发育不全)接受了强化联合抗生素治疗,包括头孢西丁(所有病例均联合庆大霉素:17例加用羧苄青霉素)。35例患者治疗前存在严重中性粒细胞减少。35例患者感染得到控制(尽管20例患者中性粒细胞减少持续存在)。未观察到局部、全身或生物学毒性。