Polterauer P, Kovarik J, Ulrich W
Wien Klin Wochenschr. 1980 Oct 10;92(19):689-93.
In 32 patients with primary liver tumors incidence and etiology of hypercalcemia were evaluated. Two patients revealed hypercalcemia from osteolytic metastases, one had coexistent primary hyperparathyroidism and in one patient hypercalcemia was paraneoplastic. The last two patients are presented in detail by case reports. Differential diagnostic problems appear often in patients in bad general condition, since invasive diagnostic methods are limited. The most potent substance to treat acute hypercalcemic syndrome is mithramycin. In those cases where surgical treatment is possible, complete resection of the primary liver tumor or the adenoma of the parathyroid gland is recommended.
对32例原发性肝肿瘤患者高钙血症的发生率和病因进行了评估。2例患者因溶骨性转移出现高钙血症，1例并存原发性甲状旁腺功能亢进，1例患者的高钙血症为副肿瘤性。最后2例患者通过病例报告详细介绍。由于侵入性诊断方法有限，一般状况较差的患者常常出现鉴别诊断问题。治疗急性高钙血症综合征最有效的药物是光辉霉素。在可行手术治疗的病例中，建议对原发性肝肿瘤或甲状旁腺腺瘤进行完整切除。
