Kao W W, Gay S, Bressan G M, Prockop D J
Artery. 1980;7(3):176-90.
Cells were isolated from the aortas of 17-day old chick embryos and they were stained with fluorescent antibodies specific for Type I collagen, Type I procollagen, Type III collagen, elastin and prolyl hydroxylase. The results indicated that the same cells simultaneously synthesize Type I procollagen, Type III procollagen and elastin. The synthesis of procollagens, and the presence of prolyl hydroxylase, in the same cells which synthesize elastin may well explain why elastin contains hydroxy-proline.
从17日龄鸡胚的主动脉中分离出细胞，并用针对I型胶原蛋白、I型前胶原蛋白、III型胶原蛋白、弹性蛋白和脯氨酰羟化酶的荧光抗体进行染色。结果表明，同一细胞同时合成I型前胶原蛋白、III型前胶原蛋白和弹性蛋白。在合成弹性蛋白的同一细胞中前胶原蛋白的合成以及脯氨酰羟化酶的存在，很可能解释了为什么弹性蛋白含有羟脯氨酸。
