视黄酸在体外的细胞摄取。
Cellular uptake of retinoic acid in vitro.
作者信息
Banerjee C K, Sani B P
出版信息
Biochem J. 1980 Sep 15;190(3):839-42. doi: 10.1042/bj1900839.
Abstract
Incubation of chick embryo skin and mouse colon tumour 26 with [3H]retinoic acid resulted in the formation of a complex of retinoic acid and its cellular binding protein both in cytosol and in nuclei. Formation of the ligand--protein complex was temperature-dependent and increased with increases in retinoic acid concentration in the incubation medium. About 3--8% of the ligand present in the cytosol was associated with the nuclei.
摘要
用[3H]视黄酸孵育鸡胚皮肤和小鼠结肠肿瘤26，结果在细胞质和细胞核中均形成了视黄酸与其细胞结合蛋白的复合物。配体-蛋白质复合物的形成依赖于温度，且随着孵育培养基中视黄酸浓度的增加而增加。细胞质中存在的约3%-8%的配体与细胞核相关联。
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