Knepel W, Anhut H, Nutto D, Hertting G
Eur J Pharmacol. 1980 Dec 5;68(3):359-63. doi: 10.1016/0014-2999(80)90533-6.
We investigated in conscious rats, whether vasopressin, whose release was stimulated by isoprenaline (i.m.), caused the simultaneous increase in plasma beta-endorphin-like immunoreactivity (beta-EI). The increase in plasma beta-EI following isoprenaline administration was diminished by about 50% in rats pretreated with a vasopressin antagonist and also in rats with a hereditary absolute lack of vasopressin. We conclude that the isoprenaline-induced release of beta-EI is mediated in part by vasopressin.
我们在清醒大鼠中研究了由异丙肾上腺素（肌肉注射）刺激释放的血管加压素是否会导致血浆β-内啡肽样免疫反应性（β-EI）同时增加。在用血管加压素拮抗剂预处理的大鼠以及遗传性完全缺乏血管加压素的大鼠中，异丙肾上腺素给药后血浆β-EI的增加减少了约50%。我们得出结论，异丙肾上腺素诱导的β-EI释放部分是由血管加压素介导的。
