Matus A, Pehling G, Wilkinson D
J Neurobiol. 1981 Jan;12(1):67-73. doi: 10.1002/neu.480120106.
Rat brain synaptic plasma membranes contain two receptorlike binding sites for the inhibitory transmitter gamma-aminobutyric acid. Postsynaptic junctional structures (postsynaptic densities) isolated from these membranes contain only the higher affinity site enriched more than sixfold compared to the membranes. The results provide the first direct evidence for the association of transmitter receptors with postsynaptic junctional sites in the brain.
大鼠脑突触质膜含有两种与抑制性递质γ-氨基丁酸结合的受体样位点。从这些膜中分离出的突触后连接结构（突触后致密物）仅含有高亲和力位点，与膜相比，其富集程度超过六倍。这些结果为递质受体与脑中突触后连接位点的关联提供了首个直接证据。
