[可移植的人细胞系J-96的核型特征，该细胞系对柯萨奇B3病毒敏感，及其衍生的亚系J-41，对该病毒具有特异性抗性]

[Karyological characteristics of the transplantable human cell line J-96, susceptible to Coxsackie B3 virus, and of its derived subline J-41, specifically resistant to this virus].

作者信息

Khesin Ia E, Amchenkova A M, Gulevich N E, Stonova N S, Narovlianskiĭ A N

出版信息

Tsitol Genet. 1981 Jan-Feb;15(1):68-73.

Abstract

The paper is concerned with comparative cytogenetic studies of human cell line J-96 and subline J-41 derived from it. Application of G-, R- and C-techniques for differential staining of chromosomes made it possible to determine both numeric and structural changes in chromosomes of the resistant subline as compared to the initial one. The mechanisms contributing to a decrease in the normal chromosome number and to appearance of new marker chromosomes in the resistant subline cells are discussed as well as the possible relation of the found chromosome changes to the loss of cell sensitivity to the Coxsackie B3 virus.

摘要

本文关注人类细胞系J - 96及其衍生亚系J - 41的比较细胞遗传学研究。应用G、R和C技术对染色体进行差异染色，得以确定抗性亚系与初始细胞系相比染色体的数量和结构变化。文中讨论了导致抗性亚系细胞中正常染色体数量减少和出现新标记染色体的机制，以及所发现的染色体变化与细胞对柯萨奇B3病毒敏感性丧失之间的可能关系。

相似文献

1

[Karyological characteristics of the transplantable human cell line J-96, susceptible to Coxsackie B3 virus, and of its derived subline J-41, specifically resistant to this virus].[可移植的人细胞系J-96的核型特征，该细胞系对柯萨奇B3病毒敏感，及其衍生的亚系J-41，对该病毒具有特异性抗性]

Tsitol Genet. 1981 Jan-Feb;15(1):68-73.

2

Comparative cytogenetic study of a continuous human cell line and its subline susceptible and resistant, respectively, to coxsackie B3 virus.对一种连续传代的人细胞系及其分别对柯萨奇B3病毒敏感和耐药的亚系进行的比较细胞遗传学研究。

Acta Virol. 1981 Jan;25(1):19-24.

3

[Karyotype change in human cell cultures in the process of the reversion of Coxsackie B virus sensitivity].[柯萨奇B病毒敏感性逆转过程中人类细胞培养的核型变化]

Vopr Virusol. 1980 May-Jun(3):311-4.

4

[Stability of C-band heterochromatin polymorphism in 2 transplantable human cell lines differing in sensitivity to Coxsackie virus B3].[两种对柯萨奇病毒B3敏感性不同的可移植人类细胞系中C带异染色质多态性的稳定性]

Tsitol Genet. 1981 Mar-Apr;15(2):31-4.

5

[Relationship between group G chromosomes, especially chromosome 21, and the sensitivity of human cells to Coxsackie B viruses].[G组染色体，尤其是21号染色体与人类细胞对柯萨奇B病毒敏感性之间的关系]

Biull Eksp Biol Med. 1978 Nov;86(11):577-9.

6

[Heterochromatinic segments in chromosomes of cultured human cells, sensitive and resistant to Coxsackie B viruses].[培养的对柯萨奇B病毒敏感和抗性的人细胞染色体中的异染色质区段]

Tsitologiia. 1980 Jan;22(1):74-8.

7

[Recovery of the sensitivity of J-41 cells to Coxsackie B3 virus by treatment with exogenous alkaline phosphatase].[通过外源性碱性磷酸酶处理恢复J-41细胞对柯萨奇B3病毒的敏感性]

Biull Eksp Biol Med. 1980 Dec;90(12):710-2.

8

[Possible localization of the gene of sensitivity of human cells to Coxsackie B virus in the short arm of chromosome 21].[人类细胞对柯萨奇B病毒敏感性基因在21号染色体短臂上的可能定位]

Biull Eksp Biol Med. 1982 Oct;94(10):105-7.

9

[Cytogenetic and virological characteristics of the initial line and clones of RH cells with various degrees of sensitivity to the tick-borne encephalitis virus].[对蜱传脑炎病毒具有不同敏感程度的RH细胞原始株及克隆株的细胞遗传学和病毒学特征]

Tsitologiia. 1988 Apr;30(4):454-9.

10

[Karyotype characteristics of continuous cell lines. II. The variability and balance of the chromosome set of M-HeLa cells].[连续细胞系的核型特征。II. M-HeLa细胞染色体组的变异性和平衡性]

Tsitologiia. 1986 Feb;28(2):193-203.

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