Nesvetov A M
Vopr Onkol. 1981;27(2):31-8.
On the material of 144 cases of early gastric cancer its two main histological types are described: enterocellular and mucoidocellular (diffuse). Both these types are differed one from the other by trends of differentiation of tumor cells with the maintained covering function of the epithelium in intestinal carcinoma and the secretory function--in mucoid one. Intestinal cancer shows the structure of adenocarcinoma and is characterized by an expansive exophytic growth. Mucoid carcinoma produces fibrous bands, chains and free cell clusters and shows an endophytic, diffuse-infiltrative growth. In intestinal and mucoid type of cancer a stable (differentiated), progressive (actively proliferating) and regressive variants can be distinguished, the development of which is closely related with local immune reactions in the gastric wall.
以144例早期胃癌为材料，描述了其两种主要组织学类型：肠细胞型和黏液细胞型（弥漫型）。这两种类型的区别在于肿瘤细胞的分化趋势，肠型癌中上皮细胞保持覆盖功能，黏液型癌中则保持分泌功能。肠型癌呈现腺癌结构，其特征为外生性膨胀性生长。黏液型癌产生纤维带、链和游离细胞团，呈现内生性、弥漫浸润性生长。在肠型和黏液型癌中，可区分出稳定（分化型）、进展（活跃增殖型）和退行型变体，其发展与胃壁局部免疫反应密切相关。
