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头颈部肿瘤的病理学:血管形成性肿瘤,第9B部分。

The pathology of head and neck tumors: vasoformative tumors, part 9B.

作者信息

Batsakis J G, Rice D H

出版信息

Head Neck Surg. 1981 Mar-Apr;3(4):326-39. doi: 10.1002/hed.2890030408.

DOI:10.1002/hed.2890030408
PMID:6260710
Abstract

There are three principal malignant vasoformative tumors that can be found in the head and neck--hemangiopericytoma, angiosarcoma, and Kaposi's sarcoma. All are uncommon and provide challenges for the pathologist and the therapist both. The histogenesis of each tumor is different. Kaposi's sarcoma has many features which suggest that it is an altered immune-response disease. Angiosarcoma is a malignancy of endothelium. Hemangiopericytoma is a tumor whose cell of origin is considered to be the perithelial pericyte. The general prognosis for patients with Kaposi's sarcoma is good. The biologic course of a hemangiopericytoma is variable and unpredictable, but there appears to be a site dependency. Angiosarcomas, particularly high grade lesions, are resistant to therapy.

摘要

头颈部可发现三种主要的恶性血管形成性肿瘤——血管外皮细胞瘤、血管肉瘤和卡波西肉瘤。所有这些肿瘤都不常见,给病理学家和治疗师都带来了挑战。每种肿瘤的组织发生都不同。卡波西肉瘤有许多特征表明它是一种免疫反应改变的疾病。血管肉瘤是内皮细胞的恶性肿瘤。血管外皮细胞瘤是一种起源细胞被认为是血管周周细胞的肿瘤。卡波西肉瘤患者的总体预后良好。血管外皮细胞瘤的生物学过程多变且不可预测,但似乎存在部位依赖性。血管肉瘤,尤其是高级别病变,对治疗有抗性。

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