对患有疱疹病毒诱发尿路结石的无特定病原体（SPF）雄性猫的细胞相关疱疹病毒和曼岛杯状病毒的血清学反应。

Serological responses to the cell associated herpesvirus and the manx calicivirus of SPF male cats with herpesvirus-induced urolithiasis.

作者信息

Fabricant C G

出版信息

Cornell Vet. 1981 Jan;71(1):59-68.

PMID:6262014

Abstract

The feline cell associated herpesvirus (CAHV), but not the Manx calicivirus, was previously reported to induce urolithiasis in specific pathogen free (SPF) cats. Serum neutralization (SN) antibody studies, reported here, revealed that the experimental SPF cats did not have SN antibodies either against the CAHV or the Manx calicivirus in preinoculation serum samples. However, all cats inoculated with the CAHV (either alone or in combination with the Manx virus) developed SN antibodies against the herpesvirus. SN antibodies against the CAHV were detected 21 days post inoculation (PI) in 7 cats, 41 days PI in 4 cats, and 89 days PI in 1 cat. Cats inoculated with the Manx calicivirus alone, or in combination with the CAHV developed SN antibodies against the calicivirus in 7 to 21 days PI with that virus.

摘要

先前有报道称，猫细胞相关疱疹病毒（CAHV）而非马恩岛杯状病毒可在无特定病原体（SPF）猫中诱发尿石症。本文报道的血清中和（SN）抗体研究显示，实验用SPF猫在接种前的血清样本中既没有针对CAHV的SN抗体，也没有针对马恩岛杯状病毒的SN抗体。然而，所有接种CAHV（单独接种或与马恩岛病毒联合接种）的猫都产生了针对疱疹病毒的SN抗体。接种后21天，7只猫检测到针对CAHV的SN抗体；接种后41天，4只猫检测到；接种后89天，1只猫检测到。单独接种马恩岛杯状病毒或与CAHV联合接种的猫，在接种该病毒后的7至21天内产生了针对杯状病毒的SN抗体。