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[针对Wistar大鼠肾小球基底膜糖蛋白的抗体肾毒性研究]

[Study of the nephrotoxicity of antibodies directed against the glomerular basement membrane glycoproteins of the Wistar rat].

作者信息

Devulder B, Bardos P, Plouvier B, Gerfaux J, Muh J P, Tacquet A

出版信息

C R Acad Hebd Seances Acad Sci D. 1976 Nov 8;283(11 D):1373-6.

PMID:62626
Abstract

The nephrotoxic activity of prepared antibodies against previously isolated glycoproteic fractions of the Rat glomerular basement membrane was studied using Masugi's model of Nephritis. This activity was determined by following the daily evolution of the proteinuria and the value of the seric complement. It seems linked to numerous factors.

摘要

利用真木肾炎模型,研究了针对先前分离的大鼠肾小球基底膜糖蛋白组分制备的抗体的肾毒性活性。通过跟踪蛋白尿的每日变化和血清补体值来确定这种活性。它似乎与许多因素有关。

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