Foster J H
Am J Surg. 1978 Mar;135(3):389-94. doi: 10.1016/0002-9610(78)90072-7.
The results achieved by liver resection for metastatic cancer in more than 400 patients have been studied in a collected review. Certain conclusions seem justified: The liver is no longer the surgeon's "no-man's-land," and local excision of metastatic tumor can achieve clinical cure in some patients. The risk-benefit ratio for hepatic resection for secondaries seems to be shifting in favor of benefit for selected patients with primary colorectal tumors. At present liver resection for tumors metastatic from pancreas, breast, lung, stomach, kidney, reproductive organs, and skin (melanoma) cannot be recommended. Liver resection may play an important part in the multi-modal therapy of children with extensive malignant disease.
一项汇总分析研究了400多名患者因转移性癌症接受肝切除手术的结果。某些结论似乎是合理的:肝脏不再是外科医生的“无人区”,转移性肿瘤的局部切除在某些患者中可实现临床治愈。对继发性肿瘤进行肝切除的风险效益比似乎正在向有利于某些原发性结直肠癌患者的方向转变。目前,不建议对源自胰腺、乳腺、肺、胃、肾、生殖器官和皮肤(黑色素瘤)的转移性肿瘤进行肝切除。肝切除在患有广泛恶性疾病的儿童的多模式治疗中可能发挥重要作用。