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子宫内膜异位症患者中不寻常的卵巢、输卵管及盆腔间皮包涵体

Unusual ovarian, tubal and pelvic mesothelial inclusions in patients with endometriosis.

作者信息

Kerner H, Gaton E, Czernobilsky B

出版信息

Histopathology. 1981 May;5(3):277-83. doi: 10.1111/j.1365-2559.1981.tb01786.x.

DOI:10.1111/j.1365-2559.1981.tb01786.x
PMID:6263781
Abstract

Unusual mesothelial inclusions were observed in ovaries, fallopian tubes and pelvic wall in six out of 57 patients with endometriosis and in none of 100 ovaries without endometriosis. Although of the same origin as the common ovarian epithelial inclusion cysts, these mesothelial inclusions were different being small, closely packed mesothelial cell nests with or without central lumina and occasionally demonstrating a pseudoinfiltrative pattern, rather than the cystically dilated, non-crowded glands lined by a variety of Müllerian type epithelia. Histochemical reactions of these mesothelial inclusions were similar to those obtained in normal mesothelium, but differed from those seen in common epithelial inclusion cysts, endometriosis and adenocarcinoma. The association of these inclusions with endometriosis suggests that a common stimulus is responsible for the development of both conditions from the multipotential pelvic mesothelium.

摘要

在57例子宫内膜异位症患者中,有6例在卵巢、输卵管和盆腔壁观察到异常间皮包涵体,而100个无子宫内膜异位症的卵巢中均未观察到。尽管这些间皮包涵体与常见的卵巢上皮包涵体囊肿起源相同,但它们有所不同,表现为小的、紧密排列的间皮细胞巢,有或无中央腔隙,偶尔呈假浸润模式,而不是由各种苗勒管型上皮衬里的囊性扩张、非拥挤的腺体。这些间皮包涵体的组织化学反应与正常间皮相似,但与常见上皮包涵体囊肿、子宫内膜异位症和腺癌不同。这些包涵体与子宫内膜异位症的关联表明,共同的刺激因素导致了盆腔多潜能间皮发生这两种情况。

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引用本文的文献

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Endometriosis is not the endometrium: Reviewing the over-representation of eutopic endometrium in endometriosis research.子宫内膜异位症并非子宫内膜:审视子宫内膜异位症研究中在位内膜过度呈现的问题。
Elife. 2025 May 20;14:e103825. doi: 10.7554/eLife.103825.
2
Association between Ovarian Endometriomas and Stage of Endometriosis.卵巢子宫内膜异位囊肿与子宫内膜异位症分期之间的关联
J Clin Med. 2024 Aug 2;13(15):4530. doi: 10.3390/jcm13154530.
3
Florid Mesothelial Hyperplasia Associated with Abdominal Wall Endometriosis Mimicking Invasive Carcinoma.
与腹壁子宫内膜异位症相关的弥漫性间皮增生,酷似浸润性癌。
Case Rep Pathol. 2021 Nov 28;2021:3439700. doi: 10.1155/2021/3439700. eCollection 2021.
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Molecular aspects of development and regulation of endometriosis.子宫内膜异位症发生发展及调控的分子机制
Reprod Biol Endocrinol. 2014 Jun 13;12:50. doi: 10.1186/1477-7827-12-50.
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Ultrastructure of ectopic peritoneal lesions from women with endometriosis, including observations on the contribution of coelomic mesothelium.子宫内膜异位症女性异位腹膜病变的超微结构,包括关于体腔间皮贡献的观察
Reprod Sci. 2009 Jan;16(1):43-55. doi: 10.1177/1933719108324891. Epub 2008 Nov 14.
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Simultaneous occurrence of herniated disc and mesothelial cyst in a 16-year-old male.一名16岁男性同时出现椎间盘突出和间皮囊肿。
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