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家兔肝门静脉的神经支配:反对“嘌呤能”神经传递的超微结构证据。

The innervation of the hepatic portal vein in the rabbit: ultrastructural evidence against "purinergic" neurotransmission.

作者信息

Gibbins I L

出版信息

Cell Tissue Res. 1981;217(3):563-7. doi: 10.1007/BF00219364.

DOI:10.1007/BF00219364
PMID:6265092
Abstract

The relative density of adrenergic and non-adrenergic nerves in the hepatic portal vein of the rabbit has been determined ultrastructurally. Adrenergic nerves were visualised with the modified chromaffin procedure of Tranzer and Richards (1976). Nearly equal numbers of adrenergic and non-adrenergic nerve profiles were found, indicating a much greater density of innervation by non-adrenergic nerves than that described by Burnstock et al. (1979) using light microscopic histochemical methods. These results imply that part of the argument used by Burnstock et al. (1979) to support "purinergic" transmission in rabbit portal vein is probably invalid.

摘要

已通过超微结构测定了兔肝门静脉中肾上腺素能神经和非肾上腺素能神经的相对密度。采用Tranzer和Richards(1976年)改良的嗜铬细胞法使肾上腺素能神经可视化。发现肾上腺素能神经和非肾上腺素能神经纤维的数量几乎相等,这表明非肾上腺素能神经的神经支配密度比Burnstock等人(1979年)使用光学显微镜组织化学方法所描述的要高得多。这些结果表明,Burnstock等人(1979年)用于支持兔门静脉中“嘌呤能”传递的部分论据可能是无效的。

相似文献

1
The innervation of the hepatic portal vein in the rabbit: ultrastructural evidence against "purinergic" neurotransmission.家兔肝门静脉的神经支配:反对“嘌呤能”神经传递的超微结构证据。
Cell Tissue Res. 1981;217(3):563-7. doi: 10.1007/BF00219364.
2
Comparative pharmacological and histochemical evidence for purinergic inhibitory innervation of the portal vein of the rabbit, but not guinea-pig.关于嘌呤能抑制性神经支配存在于兔门静脉而非豚鼠门静脉的比较药理学和组织化学证据。
Br J Pharmacol. 1979 Mar;65(3):377-88. doi: 10.1111/j.1476-5381.1979.tb07841.x.
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Br J Pharmacol. 1993 Jul;109(3):606-8. doi: 10.1111/j.1476-5381.1993.tb13614.x.

引用本文的文献

1
Lack of correlation between ultrastructural and pharmacological types of non-adrenergic autonomic nerves.非肾上腺素能自主神经的超微结构类型与药理类型之间缺乏相关性。
Cell Tissue Res. 1982;221(3):551-81. doi: 10.1007/BF00215701.

本文引用的文献

1
An analysis of the responses of the isolated portal vein of the rabbit to electrical stimulation and to drugs.兔离体门静脉对电刺激和药物反应的分析。
Br J Pharmacol Chemother. 1967 May;30(1):46-66. doi: 10.1111/j.1476-5381.1967.tb02112.x.
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The fine structure of smooth muscle cells and their relationship to connective tissue in the rabbit portal vein.兔门静脉平滑肌细胞的精细结构及其与结缔组织的关系。
Cell Tissue Res. 1980;210(2):257-67. doi: 10.1007/BF00237614.
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Peptidergic neurones.肽能神经元。
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Some properties of the smooth muscle of rabbit portal vein.兔门静脉平滑肌的一些特性。
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Purinergic nerves.嘌呤能神经
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Relaxations of the isolated portal vein of the rabbit induced by nicotine and electrical stimulation.尼古丁和电刺激对兔离体门静脉的舒张作用
Br J Pharmacol. 1970 Jul;39(3):476-89. doi: 10.1111/j.1476-5381.1970.tb10356.x.
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Distribution of adrenergic nerves and changes in neuromuscular transmission in the mouse vas deferens during postnatal development.小鼠输精管在出生后发育过程中肾上腺素能神经的分布及神经肌肉传递的变化。
Dev Biol. 1970 Apr;21(4):491-505. doi: 10.1016/0012-1606(70)90074-6.
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Comparative pharmacological and histochemical evidence for purinergic inhibitory innervation of the portal vein of the rabbit, but not guinea-pig.关于嘌呤能抑制性神经支配存在于兔门静脉而非豚鼠门静脉的比较药理学和组织化学证据。
Br J Pharmacol. 1979 Mar;65(3):377-88. doi: 10.1111/j.1476-5381.1979.tb07841.x.
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Quinacrine affinity of endocrine cell systems containing dense core vesicles as visualized by fluorescence microscopy.通过荧光显微镜观察含有致密核心囊泡的内分泌细胞系统的喹吖因亲和力。
Cell Tissue Res. 1979 Dec;204(2):171-86. doi: 10.1007/BF00234631.
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Ultrastructural cytochemistry of biogenic amines in nervous tissue: methodologic improvements.神经组织中生物胺的超微结构细胞化学:方法学改进
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