狒狒（豚尾狒狒）的癫痫与睡眠结构

Epilepsy and sleep organization in the baboon Papio papio.

作者信息

Tanaka T, Naquet R

出版信息

Electroencephalogr Clin Neurophysiol. 1976 Dec;41(6):580-6. doi: 10.1016/0013-4694(76)90003-1.

Abstract

Effects of different types of epileptic seizure on the sleep organization of baboon were studied through 12 h polygraphic recordings. Photically induced myoclonic jerking did not modify sleep organization. Photically induced genalized convulsions produced an increase of the waking stage (AWA) and reduction of REM stage. Pentetrazol-induced generalized convulsions not only increased AWA and reduced REM, but also elicited various modifications of stages I, II and III. Daily generalized convulsions induced by light or pentetrazol over 5 days demonstrated no rebound of REM.

摘要

通过12小时的多导睡眠图记录，研究了不同类型癫痫发作对狒狒睡眠结构的影响。光诱导的肌阵挛性抽搐未改变睡眠结构。光诱导的全身性惊厥导致觉醒期（AWA）增加，快速眼动期（REM）减少。戊四氮诱导的全身性惊厥不仅增加了AWA并减少了REM，还引起了I、II和III期的各种改变。连续5天由光或戊四氮诱导的每日全身性惊厥未显示REM的反弹。