在卵磷脂形成有缺陷的动物细胞突变体中热不稳定的CDP-胆碱合成酶。 - Suppr

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超能文献

Thermolabile CDP-choline synthetase in an animal cell mutant defective in lecithin formation.

作者信息

Esko J D, Wermuth M M, Raetz C R

出版信息

J Biol Chem. 1981 Jul 25;256(14):7388-93.

PMID:6265447

Abstract

摘要

相似文献

Thermolabile CDP-choline synthetase in an animal cell mutant defective in lecithin formation.在卵磷脂形成有缺陷的动物细胞突变体中热不稳定的CDP-胆碱合成酶。

J Biol Chem. 1981 Jul 25;256(14):7388-93.

Autoradiographic detection of animal cell membrane mutants altered in phosphatidylcholine synthesis.通过放射自显影检测磷脂酰胆碱合成中发生改变的动物细胞膜突变体。

Proc Natl Acad Sci U S A. 1980 Sep;77(9):5192-6. doi: 10.1073/pnas.77.9.5192.

Alteration in the characters of CDP-choline synthetase and phospholipid-choline exchange enzyme upon choline starvation in Chinese hamster ovary cells.

J Biol Chem. 1985 May 25;260(10):5925-30.

Regulation of phosphatidylcholine biosynthesis in Chinese hamster ovary cells by reversible membrane association of CTP: phosphocholine cytidylyltransferase.CTP：磷酸胆碱胞苷转移酶的可逆膜结合对中国仓鼠卵巢细胞中磷脂酰胆碱生物合成的调控

J Biol Chem. 1985 Jul 5;260(13):7919-26.

Expression of phosphatidylethanolamine N-methyltransferase-2 cannot compensate for an impaired CDP-choline pathway in mutant Chinese hamster ovary cells.磷脂酰乙醇胺N-甲基转移酶-2的表达无法弥补突变型中国仓鼠卵巢细胞中受损的CDP-胆碱途径。

J Biol Chem. 1995 Jul 7;270(27):16277-82. doi: 10.1074/jbc.270.27.16277.

Regulation of phosphatidylcholine biosynthesis in mammalian cells. III. Effects of alterations in the phospholipid compositions of Chinese hamster ovary and LM cells on the activity and distribution of CTP:phosphocholine cytidylyltransferase.哺乳动物细胞中磷脂酰胆碱生物合成的调控。III. 中国仓鼠卵巢细胞和LM细胞磷脂组成的改变对CTP：磷酸胆碱胞苷转移酶活性和分布的影响。

J Biol Chem. 1983 Jan 25;258(2):836-9.

Regulation of phosphatidylcholine biosynthesis in mammalian cells. II. Effects of phospholipase C treatment on the activity and subcellular distribution of CTP:phosphocholine cytidylyltransferase in Chinese hamster ovary and LM cell lines.哺乳动物细胞中磷脂酰胆碱生物合成的调控。II. 磷脂酶C处理对中国仓鼠卵巢细胞和LM细胞系中CTP：磷酸胆碱胞苷转移酶活性及亚细胞分布的影响

J Biol Chem. 1983 Jan 25;258(2):831-5.

Regulation of phosphatidylcholine biosynthesis in mammalian cells. I. Effects of phospholipase C treatment on phosphatidylcholine metabolism in Chinese hamster ovary cells and LM mouse fibroblasts.哺乳动物细胞中磷脂酰胆碱生物合成的调控。I. 磷脂酶C处理对中国仓鼠卵巢细胞和LM小鼠成纤维细胞中磷脂酰胆碱代谢的影响。

J Biol Chem. 1983 Jan 25;258(2):824-30.

Animal cells dependent on exogenous phosphatidylcholine for membrane biogenesis.动物细胞的膜生物合成依赖于外源性磷脂酰胆碱。

Proc Natl Acad Sci U S A. 1982 Mar;79(6):1698-702. doi: 10.1073/pnas.79.6.1698.

Yeast mutant with thermolabile CDP-choline synthesis. Isolation and characterization of a cholinephosphate cytidyltransferase mutant.具有热不稳定CDP-胆碱合成能力的酵母突变体。磷酸胆碱胞苷转移酶突变体的分离与鉴定。

Eur J Biochem. 1983 Mar 1;131(1):223-9. doi: 10.1111/j.1432-1033.1983.tb07253.x.

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Differential dephosphorylation of CTP:phosphocholine cytidylyltransferase upon translocation to nuclear membranes and lipid droplets.在向核膜和脂滴转运时，CTP：磷酸胆堿胞苷转移酶的差向去磷酸化。

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Heterologous expression of CTP:phosphocholine cytidylyltransferase from Plasmodium falciparum rescues Chinese Hamster Ovary cells deficient in the Kennedy phosphatidylcholine biosynthesis pathway.疟原虫 CTP：磷酸胆碱胞苷转移酶的异源表达挽救了 Kennedy 磷脂酰胆碱生物合成途径缺陷的中国仓鼠卵巢细胞。

Sci Rep. 2018 Jun 12;8(1):8932. doi: 10.1038/s41598-018-27183-w.

Molecular Mechanism for the Thermo-Sensitive Phenotype of CHO-MT58 Cell Line Harbouring a Mutant CTP:Phosphocholine Cytidylyltransferase.携带突变型CTP：磷酸胆碱胞苷转移酶的CHO-MT58细胞系热敏表型的分子机制

PLoS One. 2015 Jun 17;10(6):e0129632. doi: 10.1371/journal.pone.0129632. eCollection 2015.

Depletion of phosphatidylcholine affects endoplasmic reticulum morphology and protein traffic at the Golgi complex.磷脂酰胆碱的耗竭会影响内质网形态和高尔基体复合物中的蛋白质运输。

J Lipid Res. 2009 Nov;50(11):2182-92. doi: 10.1194/jlr.M800660-JLR200. Epub 2009 May 20.

CTP:phosphocholine cytidylyltransferase alpha is required for B-cell proliferation and class switch recombination.CTP：磷酸胆碱胞苷酰转移酶α是B细胞增殖和类别转换重排所必需的。

J Biol Chem. 2009 Mar 13;284(11):6847-54. doi: 10.1074/jbc.M807338200. Epub 2009 Jan 12.

Nuclear export of the rate-limiting enzyme in phosphatidylcholine synthesis is mediated by its membrane binding domain.磷脂酰胆碱合成中限速酶的核输出由其膜结合结构域介导。

J Lipid Res. 2009 May;50(5):966-76. doi: 10.1194/jlr.M800632-JLR200. Epub 2008 Dec 20.

Expansion of the nucleoplasmic reticulum requires the coordinated activity of lamins and CTP:phosphocholine cytidylyltransferase alpha.核质网的扩张需要核纤层蛋白和CTP：磷酸胆碱胞苷转移酶α的协同作用。

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Role of phosphocholine cytidylyltransferase alpha in lung development.磷酸胆碱胞苷酰转移酶α在肺发育中的作用。

Mol Cell Biol. 2007 Feb;27(3):975-82. doi: 10.1128/MCB.01512-06. Epub 2006 Nov 27.

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