非甾体雌激素的构象分析：构象异构体群体对中-己烯雌酚和外消旋己烯雌酚与雌激素受体结合亲和力的影响。 - Suppr

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超能文献

Conformational analysis of nonsteroidal estrogens: The effect of conformer populations on the binding affinity of meso- and dl-hexestrol to the estrogen receptor.

作者信息

Kilbourn M R, Arduengo A J, Park J T, Katzenellenbogen J A

出版信息

Mol Pharmacol. 1981 May;19(3):388-98.

PMID:6267445

Abstract

摘要

相似文献

Conformational analysis of nonsteroidal estrogens: The effect of conformer populations on the binding affinity of meso- and dl-hexestrol to the estrogen receptor.非甾体雌激素的构象分析：构象异构体群体对中-己烯雌酚和外消旋己烯雌酚与雌激素受体结合亲和力的影响。

Mol Pharmacol. 1981 May;19(3):388-98.

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Nonsteroidal estrogens: synthesis and estrogen receptor binding affinity of derivatives of (3R*,4S*)-3,4-bis(4-hydroxyphenyl)hexane (hexestrol) and (2R*,3S*)-2,3-bis(4-hydroxyphenyl)pentane (norhexestrol) functionalized on the side chain.

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Metabolic activation and formation of DNA adducts of hexestrol, a synthetic nonsteroidal carcinogenic estrogen.己烷雌酚（一种合成的非甾体致癌雌激素）的代谢活化及DNA加合物的形成

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Synthesis, receptor binding, and target-tissue uptake of carbon-11 labeled carbamate derivatives of estradiol and hexestrol.雌二醇和己烯雌酚的碳-11标记氨基甲酸酯衍生物的合成、受体结合及靶组织摄取

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(2R*, 3S*)-1-[18F]fluoro-2,3-bis(4-hydroxyphenyl)pentane [( 18F]fluoronor-hexestrol), a positron-emitting estrogen that shows highly-selective, receptor-mediated uptake by target tissues in vivo.

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Estrogenic affinity labels: synthesis, irreversible receptor binding, and bioactivity of aziridine-substituted hexestrol derivatives.

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Preparation, receptor binding, and fluorescence properties of hexestrol-fluorophore conjugates: evaluation of site of attachment, fluorophore structure, and fluorophore-ligand spacing.己烷雌酚-荧光团缀合物的制备、受体结合及荧光特性：连接位点、荧光团结构和荧光团-配体间距的评估

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Receptor-binding radiopharmaceuticals for imaging breast tumors: estrogen-receptor interactions and selectivity of tissue uptake of halogenated estrogen analogs.

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