Mirzoian S A, Akopian V P
Biull Eksp Biol Med. 1978 Jan;85(1):45-8.
Shifts in the system of GABA transformation in ischemia and specific inhibition of GABA-transaminase under conditions of quantitative measurement of the blood circulation by means of hydrogen clearance permitted to establish a definite association between the increased GABA level in the brain and the tissues of the wall of its arteries, and the development of compensation of disturbed cerebral circulation. Consequently, one of the principal manifestations of an increased amount of endogenous GABA in deficiency of the brain blood supply was GABA capacity to improve the cerebral circulation.
在缺血状态下GABA转化系统的变化以及在通过氢清除法对血液循环进行定量测量的条件下对GABA转氨酶的特异性抑制，使得能够确定大脑及其动脉壁组织中GABA水平升高与脑循环紊乱代偿发展之间的明确关联。因此，脑供血不足时内源性GABA量增加的主要表现之一是GABA具有改善脑循环的能力。
