DeFelice R, Johnson D G, Galgiani J N
Antimicrob Agents Chemother. 1981 Jun;19(6):1073-4. doi: 10.1128/AAC.19.6.1073.
Three of forty men developed bilateral gynecomastia upon ketoconazole treatment. Symptoms abated despite continued therapy. This appears to be a direct drug effect on breast tissue.
40名男性中有3名在接受酮康唑治疗后出现双侧乳腺增生。尽管继续治疗,症状仍有所减轻。这似乎是药物对乳腺组织的直接作用。