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[血细胞性结核病中NAD-糖苷水解酶、酸性和碱性磷酸酶活性的改变]

[Alteration in activities of NAD-glycohydrolase, acid and alkaline phosphatases in blood cells tuberculosis].

作者信息

Grigorian V G, Shinkareva T I, Kiroshka V S, Tsymbalar' G G, Vangeli L V

出版信息

Vopr Med Khim. 1981 Mar-Apr;27(2):185-9.

PMID:6269296
Abstract

Activities of NAD-glyconydrolase from erythrocytes, alkaline and acid phosphatases from neutrophiles and acid phosphatase from lymphocytes were studied in patients with pulmonary tuberculosis as well as in experimental animals. Distinct alterations in the activity of the enzymes studied were observed in blood cells of guinea pigs inoculated with tuberculosis. In patients with active pulmonary tuberculosis activities of acid and alkaline phosphatases were altered in leukocytes and the activity of NAD-glycohydrolase--in erythrocytes. Inactive forms of tuberculosis were accompanied by a slight alterations in the alkaline phosphatase activity, activities of acid phosphatase and NAD-glycohydrolase were unaltered.

摘要

对肺结核患者以及实验动物的红细胞中NAD - 糖苷水解酶、嗜中性粒细胞中的碱性和酸性磷酸酶以及淋巴细胞中的酸性磷酸酶的活性进行了研究。在接种结核杆菌的豚鼠血细胞中观察到所研究酶活性的明显改变。在活动性肺结核患者中,白细胞中酸性和碱性磷酸酶的活性发生改变,而红细胞中NAD - 糖苷水解酶的活性发生改变。非活动性肺结核伴有碱性磷酸酶活性的轻微改变,酸性磷酸酶和NAD - 糖苷水解酶的活性未改变。

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