Van Duuren B L, Smith A C, Melchionne S M
Cancer Res. 1978 Mar;38(3):865-6.
Life table analysis curves have been constructed for some of the data presented in a previous report on the effect of aging and of the interval between primary and secondary treatment in two-stage carcinogenesis on mouse skin. These curves are compared with those in a recent report from another laboratory also concerning aging and skin carcinogenesis. While comparison was difficult due to differences in experimental protocol, our conclusion that age at the onset of secondary treatment is of overriding importance in determining final tumor yields is substantiated.
已根据先前一份报告中呈现的部分数据构建了生命表分析曲线，该报告探讨了衰老以及两阶段致癌过程中初级治疗和次级治疗间隔对小鼠皮肤的影响。这些曲线与另一个实验室最近一份同样关于衰老和皮肤致癌的报告中的曲线进行了比较。尽管由于实验方案的差异难以进行比较，但我们得出的结论得到了证实，即在确定最终肿瘤产量方面，次级治疗开始时的年龄至关重要。
