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A partial view of the mechanism of insulin action.

作者信息

Denton R M, Brownsey R W, Belsham G J

出版信息

Diabetologia. 1981 Oct;21(4):347-62. doi: 10.1007/BF00252681.

DOI:10.1007/BF00252681
PMID:6269936
Abstract
摘要

相似文献

1
A partial view of the mechanism of insulin action.胰岛素作用机制的部分观点。
Diabetologia. 1981 Oct;21(4):347-62. doi: 10.1007/BF00252681.
2
Molecular events in the action of insulin on cell metabolism. The significance of cyclic AMP dependent protein kinases.胰岛素对细胞代谢作用中的分子事件。环磷酸腺苷依赖性蛋白激酶的意义。
Acta Endocrinol Suppl (Copenh). 1974;191:93-129. doi: 10.1530/acta.0.077s0093.
3
Cyclic adenosine monophosphate and clinical medicine. 2. Carbohydrate and lipid metabolism.环磷酸腺苷与临床医学。2. 碳水化合物与脂质代谢。
Am J Med Sci. 1974 Aug;268(2):62-91. doi: 10.1097/00000441-197408000-00001.
4
Intracellular mediators of insulin action.
Annu Rev Physiol. 1985;47:405-24. doi: 10.1146/annurev.ph.47.030185.002201.
5
Protein phosphorylation catalyzed by cyclic AMP-dependent and cyclic GMP-dependent protein kinases.由环磷酸腺苷依赖性蛋白激酶和环磷酸鸟苷依赖性蛋白激酶催化的蛋白质磷酸化作用。
Annu Rev Pharmacol Toxicol. 1980;20:363-88. doi: 10.1146/annurev.pa.20.040180.002051.
6
Cyclic nucleotide-binding domains in proteins having diverse functions.
J Biol Chem. 1992 Mar 25;267(9):5723-6.
7
A multifunctional cyclic nucleotide- and Ca2+-independent protein kinase from rabbit skeletal muscle.
Biochem Biophys Res Commun. 1982 Jul 30;107(2):676-83. doi: 10.1016/0006-291x(82)91544-3.
8
Compartmentation of second messenger action: immunocytochemical and biochemical evidence.第二信使作用的区室化：免疫细胞化学和生物化学证据。
Vitam Horm. 1985;42:197-252. doi: 10.1016/s0083-6729(08)60063-1.
9
Membrane phospholipid metabolism and signal transduction for protein phosphorylation.膜磷脂代谢与蛋白质磷酸化的信号转导。
Adv Cyclic Nucleotide Protein Phosphorylation Res. 1984;18:119-58.
10
[Protein phosphorylation in the brain].[大脑中的蛋白质磷酸化]
Tanpakushitsu Kakusan Koso. 1990 May;35(7 Suppl):1054-63.

引用本文的文献

1
Thiazolidinediones: effects on insulin resistance and the cardiovascular system.噻唑烷二酮类药物：对胰岛素抵抗和心血管系统的影响。
Br J Pharmacol. 2008 Feb;153(4):636-45. doi: 10.1038/sj.bjp.0707452. Epub 2007 Oct 1.
2
Insulin-stimulated phosphorylation of lipin mediated by the mammalian target of rapamycin.雷帕霉素哺乳动物靶点介导的胰岛素刺激的脂素磷酸化。
Proc Natl Acad Sci U S A. 2002 Jan 22;99(2):1047-52. doi: 10.1073/pnas.022634399. Epub 2002 Jan 15.
3
Hormonal regulation of physiological cell turnover and apoptosis.生理细胞更新与凋亡的激素调节。

本文引用的文献

1
The action of insulin on the distribution of galactose in eviscerated nephrectomized dogs.胰岛素对去内脏切除肾脏的狗体内半乳糖分布的作用。
J Biol Chem. 1949 Jun;179(2):985.
2
GLUCOSE UPTAKE BY INCUBATED RAT EPIDIDYMAL ADIPOSE TISSUE. RATE-LIMITING STEPS AND SITE OF INSULIN ACTION.孵育的大鼠附睾脂肪组织对葡萄糖的摄取。限速步骤及胰岛素作用位点。
J Biol Chem. 1965 Jan;240:14-21.
3
Chemistry of insulin; determination of the structure of insulin opens the way to greater understanding of life processes.胰岛素的化学性质；胰岛素结构的确定为更深入理解生命过程开辟了道路。
Cell Tissue Res. 2000 Jul;301(1):101-24. doi: 10.1007/s004419900159.
4
Insulin-stimulated kinase from rat fat cells that phosphorylates initiation factor 4E-binding protein 1 on the rapamycin-insensitive site (serine-111).来自大鼠脂肪细胞的胰岛素刺激激酶，其可在雷帕霉素不敏感位点（丝氨酸-111）使起始因子4E结合蛋白1磷酸化。
Biochem J. 1998 Nov 15;336 ( Pt 1)(Pt 1):39-48. doi: 10.1042/bj3360039.
5
Molecular mechanisms for the control of translation by insulin.胰岛素调控翻译的分子机制。
Biochem J. 1997 Dec 1;328 ( Pt 2)(Pt 2):329-41. doi: 10.1042/bj3280329.
6
Extracellular calcium modulates insulin's action on enzymes controlling cyclic AMP metabolism in intact hepatocytes.细胞外钙可调节胰岛素对完整肝细胞中控制环磷酸腺苷代谢的酶的作用。
Biochem J. 1993 Jul 1;293 ( Pt 1)(Pt 1):249-53. doi: 10.1042/bj2930249.
7
Molecular cloning and tissue distribution of PHAS-I, an intracellular target for insulin and growth factors.胰岛素和生长因子的细胞内靶点PHAS-I的分子克隆及组织分布
Proc Natl Acad Sci U S A. 1994 Apr 26;91(9):3730-4. doi: 10.1073/pnas.91.9.3730.
8
cAMP- and rapamycin-sensitive regulation of the association of eukaryotic initiation factor 4E and the translational regulator PHAS-I in aortic smooth muscle cells.环磷酸腺苷（cAMP）和雷帕霉素敏感性调节真核生物起始因子4E与主动脉平滑肌细胞中翻译调节因子PHAS-I的结合
Proc Natl Acad Sci U S A. 1995 Aug 1;92(16):7222-6. doi: 10.1073/pnas.92.16.7222.
9
Reversibility of the insulin-stimulated phosphorylation of ATP citrate lyase and a cytoplasmic protein of subunit Mr 22000 in adipose tissue.脂肪组织中胰岛素刺激的ATP柠檬酸裂解酶及一种22000亚基细胞质蛋白磷酸化的可逆性。
Biochem J. 1982 Apr 15;204(1):345-52. doi: 10.1042/bj2040345.
10
Preliminary characterization of a heat-stable protein from rat adipose tissue whose phosphorylation is stimulated by insulin.来自大鼠脂肪组织的一种热稳定蛋白的初步特性，其磷酸化受胰岛素刺激。
Biochem J. 1982 Jun 15;204(3):817-24. doi: 10.1042/bj2040817.
Science. 1959 May 15;129(3359):1340-4. doi: 10.1126/science.129.3359.1340.
4
Insulin action on the adenyl cyclase system: Antagonism to activation by lipolytic hormones.胰岛素对腺苷酸环化酶系统的作用：对脂解激素激活作用的拮抗。
FEBS Lett. 1972 Feb 1;20(2):191-194. doi: 10.1016/0014-5793(72)80791-9.
5
Incorporation of [32P]phosphate into the pyruvate dehydrogenase complex in rat heart mitochondria.[32P]磷酸盐掺入大鼠心脏线粒体丙酮酸脱氢酶复合物的研究。
Biochem J. 1980 May 15;188(2):409-21. doi: 10.1042/bj1880409.
6
Regulation of adipose tissue lipolysis: phosphorylation of hormones sensitive lipase in intact rat adipocytes.脂肪组织脂解作用的调节：完整大鼠脂肪细胞中激素敏感性脂肪酶的磷酸化
FEBS Lett. 1980 Feb 25;111(1):120-4. doi: 10.1016/0014-5793(80)80775-7.
7
Occupancy of sites of phosphorylation in inactive rat heart pyruvate dehydrogenase phosphate in vivo.体内失活大鼠心脏丙酮酸脱氢酶磷酸化位点的占据情况。
Biochem J. 1981 Mar 1;193(3):935-46. doi: 10.1042/bj1930935.
8
Studies on the incorporation of [32P]phosphate into pyruvate dehydrogenase in intact rat fat-cells. Effects of insulin.关于[32P]磷酸盐掺入完整大鼠脂肪细胞中丙酮酸脱氢酶的研究。胰岛素的作用。
Biochem J. 1980 Nov 15;192(2):469-81. doi: 10.1042/bj1920469.
9
Activation of the pyruvate dehydrogenase complex in isolated fat cell mitochondria by hydrogen peroxide and t-butyl hydroperoxide.过氧化氢和叔丁基过氧化氢对分离的脂肪细胞线粒体中丙酮酸脱氢酶复合物的激活作用。
FEBS Lett. 1980 Dec 15;122(1):29-32. doi: 10.1016/0014-5793(80)80394-2.
10
Partial purification from rat adipocyte plasma membranes of a chemical mediator which simulates the action of insulin on pyruvate dehydrogenase.从大鼠脂肪细胞质膜中部分纯化出一种化学介质，该介质可模拟胰岛素对丙酮酸脱氢酶的作用。
J Biol Chem. 1981 Mar 25;256(6):2945-51.