Himon F, Job J C, Pierson M, Canlorbe P
Sem Hop. 1981;57(37-38):1488-93.
A study of 52 pubertal patients having been treated for virilizing adrenal hyperplasia (38 females and 14 males) leads to emphasize the importance of the precocity and accuracy of treatment. In patients with delayed treatment, mainly when they are girls, an advanced or true precocious puberty will increase the advance of bone age and reduce adult height. But, whatever be the time of onset of treatment and of pubertal achievement, no important or sustained sexual improvement was found in patients receiving a well-controlled treatment.
一项对52例接受过男性化肾上腺增生治疗的青春期患者（38名女性和14名男性）的研究强调了治疗的早熟性和准确性的重要性。在治疗延迟的患者中，主要是女孩，性早熟或真性性早熟会加速骨龄进展并降低成年身高。但是，无论治疗开始时间和青春期发育时间如何，接受良好控制治疗的患者均未发现明显或持续的性征改善。
