Lamouliatte H, Plane D, Quinton A
Sem Hop. 1981;57(37-38):1499-503.
There is a hypophosphoremic syndrome first discovered without parenteral nutrition (TPN) then on patients with TPN. It appears preferentially in patients suffering from denutrition and receiving an important caloric intake, particularly with glucose. Clinical picture associates psychic, neurologic and respiratory disorders. Phosphatemia is often below 10 mg/l or 0,33 mmol/l, with decrease or even disappearance of phosphatemia. The mechanism is still baby known. During TPN, it occurs an intra-cellular passage of phosphate whose consequences are anomalies in red blood cell metabolism, with decrease of tissular oxygenation, in white cell function, platelet function, central nervous system, muscle, liver and acid-base equilibrium. Treatment must be first preventive with careful control of phosphatemia and systematic intake of phosphates. Curative treatment associates correction of hypophosphatemia and simultaneous decrease of caloric intake.
有一种低磷血症综合征，最初是在未接受肠外营养（TPN）的患者中发现，后来在接受TPN的患者中也有发现。它优先出现在营养不良且摄入高热量，尤其是葡萄糖的患者中。临床表现伴有精神、神经和呼吸障碍。血磷水平常低于10mg/l或0.33mmol/l，血磷降低甚至消失。其机制仍鲜为人知。在TPN期间，会发生细胞内磷酸盐转移，其后果是红细胞代谢异常，组织氧合减少，白细胞功能、血小板功能、中枢神经系统、肌肉、肝脏和酸碱平衡出现异常。治疗首先必须进行预防，仔细控制血磷水平并系统摄入磷酸盐。治疗性治疗包括纠正低磷血症并同时减少热量摄入。
