Evers K G, Bliesener J A
Eur J Pediatr. 1978 Jan 17;127(2):127-32. doi: 10.1007/BF00445768.
A ten month old female Turkish child with chylous ascites, diarrhea, steatorrhea, peripheral edema and hypoproteinemia was investigated for protein losing enteropathy which probably dated from the first weeks of life. Gastrointestinal protein loss appeared to be due to abnormalities of the intestinal lymphatics. In order to detect a localized lymphoenteric fistula, lymphangiography was tried but failed due to hypoplasia of peripheral lymphatics. However, three hours after intradermal injection of Patent Blue, the dye appeared in the stools of the patient, suggesting intestinal protein loss via a lympho-enteric fistula. This observation may provide the basis for a diagnostic test for gastro-intestinal protein loss in patients with intestinal lymphangiectasia.
一名10个月大的土耳其女婴，患有乳糜性腹水、腹泻、脂肪泻、外周水肿和低蛋白血症，因可能自出生第一周起就存在的蛋白丢失性肠病而接受检查。胃肠道蛋白丢失似乎是由于肠道淋巴管异常所致。为了检测局部淋巴肠瘘，尝试了淋巴管造影，但由于外周淋巴管发育不全而失败。然而，在皮内注射专利蓝3小时后，染料出现在患者粪便中，提示存在通过淋巴肠瘘导致的肠道蛋白丢失。这一观察结果可能为诊断肠道淋巴管扩张症患者胃肠道蛋白丢失的检测试验提供依据。
