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在被多种2型单纯疱疹病毒株有效感染的细胞中微管呈现出一致性外观。

Consistent appearance of microtubules in cells productively infected with various strains of type 2 herpes simplex virus.

作者信息

Nii S, Yasuda Y, Kurata T, Aoyama Y

出版信息

Biken J. 1981 Jun;24(1-2):81-7.

PMID:6272691
Abstract

Electron microscopic examination showed microtubular structures in FL cells infected with all 18 strains of HSV-2 examined, but not in cells infected with 9 strains of HSV-1. These structures were also detected in other cultured cells (Vero and Earle's L cells) infected with HSV-2, and also in vivo in cells, such as neuronal cells of the spinal ganglia and liver cells, of one-day-old suckling mice (DDD strain) infected with this type of virus. Thus the microtubules were consistently detected in cells productively infected with HSV-2. No other herpesviruses so far examined produced microtubular structures such as those observed in HSV-2 infected cells.

摘要

电子显微镜检查显示,在所检测的18株单纯疱疹病毒2型(HSV-2)感染的FL细胞中可见微管结构,但在9株单纯疱疹病毒1型(HSV-1)感染的细胞中未见到。在其他感染HSV-2的培养细胞(Vero细胞和Earle's L细胞)中也检测到了这些结构,并且在感染此类病毒的1日龄乳鼠(DDD品系)的细胞(如脊髓神经节神经元细胞和肝细胞)中也在体内检测到了这些结构。因此,在被HSV-2有效感染的细胞中始终能检测到微管。到目前为止,所检测的其他疱疹病毒均未产生如在HSV-2感染细胞中所观察到的微管结构。

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