In vitro metabolism of acrylonitrile to 2-cyanoethylene oxide, reaction with glutathione, and irreversible binding to proteins and nucleic acids.

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作者信息

Guengerich F P, Geiger L E, Hogy L L, Wright P L

出版信息

Cancer Res. 1981 Dec;41(12 Pt 1):4925-33.

PMID:6272984

Abstract

摘要

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In vitro metabolism of acrylonitrile to 2-cyanoethylene oxide, reaction with glutathione, and irreversible binding to proteins and nucleic acids.

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